[FRIAM] Rugged fitness landscapes

[David Breecker]

Phil, indulge a layman for a moment:  isn't auto-catalysis widely considered 
to be the origination of life, and thus evolution?

David

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----- Original Message ----- 
From: "Phil Henshaw" <sy at synapse9.com>
To: "'The Friday Morning Applied Complexity Coffee Group'" 
<friam at redfish.com>
Sent: Tuesday, September 26, 2006 5:52 AM
Subject: Re: [FRIAM] Rugged fitness landscapes


> Well, it seems to open up to a wide variety of probably both feasible
> and infeasible mechanisms.  I think for small changes to have large
> effects there needs to be developmental process, i.e. a form of feedback
> of some sort.  There are a *great* many possible means of establishing
> process feedback.  That that mechanism, having results stimulate causes,
> has been ruled out of evolution theory for over a century seems to me to
> indicate a lack of imagination.
>
>
> Phil Henshaw                       ¸¸¸¸.·´ ¯ `·.¸¸¸¸
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> 680 Ft. Washington Ave
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> e-mail: pfh at synapse9.com
> explorations: www.synapse9.com
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>
>> -----Original Message-----
>> From: friam-bounces at redfish.com
>> [mailto:friam-bounces at redfish.com] On Behalf Of Jochen Fromm
>> Sent: Tuesday, September 26, 2006 6:59 AM
>> To: 'The Friday Morning Applied Complexity Coffee Group'
>> Subject: Re: [FRIAM] Rugged fitness landscapes
>>
>>
>>
>> Yes, his work contains interesting ideas. I especially
>> like the appealing idea of correlating interdependencies
>> in the genotype with the ruggedness of fitness landscapes,
>> although it is probably to simple. Are interdependencies
>> between modules in the genotypes a reason why small changes
>> in the genotype could have large effects on reproduction
>> rates ? It seems plausible, but hard to prove.
>>
>> The fitness function depends in general on the
>> success of the phenotype (reproduction rates), and the
>> relationship between genotype and phenotype is very
>> complex and non-linear. The fitness of a phenotype
>> is easy to determine, but hard to calculate from the
>> genotype. This is similar to NP-complete problems:
>> the quality of a solution is easy to verify, but the
>> solution itself is hard to calculate. Therefore it is
>> probably hard to say how rugged the fitness landscape is
>> dependent on changes in the genotype, because the fitness
>> is an unpredictable emergent property of the whole system,
>> including the environment.
>>
>> One recent concept in this area seems to be "Epistasis"
>> http://en.wikipedia.org/wiki/Epistasis
>>
>> Epistasis and Shapes
>> of Fitness Landscapes http://arxiv.org/abs/q-bio.PE/0603034
>>
>> -J.
>>
>>
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>
>
>
> ============================================================
> FRIAM Applied Complexity Group listserv
> Meets Fridays 9a-11:30 at cafe at St. John's College
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>