[FRIAM] New information on COVID-19

[Roger Critchlow]

An "In Depth" appears in Science online today,
https://science.sciencemag.org/content/368/6490/455, titled "The mystery of
the pandemic's ‘happy hypoxia’".  It mentions the NYTimes OpEd in passing.

One suggestion is that the blood is clotting in the lung capillaries, which
interferes with O2 transport by red blood cells while allowing the plain
gas transport of CO2 to continue as normal, hence hypoxic but venting CO2
normally and not feeling in the least breathless.  24 of 27 hypoxic
patients treated with heparin (a blood thinner also used as a rat poison)
recovered well, 2 are still critical, and 1 was transferred to another
hospital.  That's a good preliminary result.

-- rec --

On Fri, Apr 24, 2020 at 11:40 AM Roger Critchlow <rec at elf.org> wrote:

>
>
> On Thu, Apr 23, 2020 at 8:32 PM Roger Critchlow <rec at elf.org> wrote:
>
>>
>> I wonder if any of those cell phone pulsimeters could be upgraded to
>> oximeters with some calibration?
>>
>
> There are a bunch of cell phone pulse oximeter apps that use the cell
> phone flash and camera, but I don't get the feeling that they've been
> calibrated much.  It's a lot easier to write the code, call it
> entertainment, and reap the ad revenues that to actually determine what the
> measurement means in the general population.  Some apps have even added
> some of the other pulse oximeter functions, perfusion, respiratory pleth,
>  Then, again, https://www.ncbi.nlm.nih.gov/pubmed/2921597 says "Smartphone-based
> pulse oximetry is not inferior to standard pulse oximetry in pediatric
> patients without hypoxia. Reliability was superior for PBA compared with
> CBA, with more precise agreement for the PBA compared with the CBA. Future
> studies should test pulse oximetry apps in a hypoxic pediatric
> population."  That was published in 2018.
>
> There's an interesting series of press releases from UIUC claiming that
> measuring someone's gait (with cellphone accelerometers) over a 6 minute
> walk is enough to get a good estimate of O_2 saturation, because people who
> aren't getting enough O_2 apparently walk funny.
>
> Here's an android app on github,
> https://github.com/YahyaOdeh/HealthWatcher, with some more method
> references, the https://github.com/topics/spo2 listing has a bunch of
> arduino projects, too.
>
> -- rec --
>
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