[FRIAM] Exciting new Covid research

glen ep ropella gepr at tempusdictum.com
Mon Sep 14 17:38:34 EDT 2020


And here's a local "Science on Tap" event:

Supercomputing and Systems Biology: A New Hypothesis for COVID-19
Dr. Daniel Jacobson https://www.ornl.gov/staff-profile/daniel-jacobson
https://www.meetup.com/ScienceOnTapORWA/events/273259319/


On 9/2/20 4:33 PM, uǝlƃ ↙↙↙ wrote:
> Thanks for sending that along!
> 
> Here's the Smmry for easy Nabble searching:
> https://smmry.com/https://elemental.medium.com/a-supercomputer-analyzed-covid-19-and-an-interesting-new-theory-has-emerged-31cb8eba9d63#&SM_LENGTH=7
> 
>> Jacobson's team says in their paper that "The pathology of Covid-19 is likely the result of Bradykinin Storms rather than cytokine storms," which had been previously identified in Covid-19 patients, but that "The two may be intricately linked." Other papers had previously identified bradykinin storms as a possible cause of Covid-19's pathologies.
>>
>> According to the researchers, bradykinin storms could create arrhythmias and low blood pressure, which are often seen in Covid-19 patients.
>>
>> Jacobson told me, "It is a reasonable hypothesis that many of the neurological symptoms in Covid-19 could be due to an excess of bradykinin. It has been reported that bradykinin would indeed be likely to increase the permeability of the blood-brain barrier. In addition, similar neurological symptoms have been observed in other diseases that result from an excess of bradykinin."
>>
>> Increased bradykinin levels could also account for other common Covid-19 symptoms.
>>
>> The similarities between ACE inhibitor side effects and Covid-19 symptoms strengthen the bradykinin hypothesis, the researchers say.
>>
>> Though still an emerging theory, the bradykinin hypothesis explains several other of Covid-19's seemingly bizarre symptoms.
>>
>> The bradykinin hypothesis provides a model that "Contributes to a better understanding of Covid-19" and "Adds novelty to the existing literature," according to scientists Frank van de Veerdonk, Jos WM van der Meer, and Roger Little, who peer-reviewed the team's paper.
> 
> 
> 
> On 9/2/20 11:04 AM, Merle Lefkoff wrote:
>> https://elemental.medium.com/a-supercomputer-analyzed-covid-19-and-an-interesting-new-theory-has-emerged-31cb8eba9d63
> 

-- 
glen ep ropella 971-599-3737



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