[FRIAM] stranger than fiction

Jon Zingale jonzingale at gmail.com
Tue Jul 26 21:47:50 EDT 2022


"""Current in silico software is only accessible to large pharmaceutical
companies willing to pay obnoxious licensing fees. Students in every
country no matter their university, startup companies to Fortune 500s, and
even dedicated hobbyists will all have the same opportunity to design new
molecules to change the future of drug discovery," said Shkreli, co-founder
of Druglike."""

FWIW, my company's software is free to academics. This article hides the
fact that the majority of the economic barrier to entry is not licensing
but the cost of performing the large-scale simulations necessary to do
docking, md, generating conformers, or what-have-you. Drug discovery is
computationally hard and if AWS or whoever is going to ultimately charge
for compute then someone along the path will need to pay for that compute.
Just my two cents.
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