<html>
  <head>
    <meta http-equiv="Content-Type" content="text/html; charset=UTF-8">
  </head>
  <body text="#000000" bgcolor="#FFFFFF">
    <p>Glen -</p>
    <p>Another interesting question to speculate around (as usual)!</p>
    <p>On the face of it, the question of whether there are brain
      changes in response to therapy or pharmaceuticals, would seem to
      be very trite or another form of the mind/body (mind/brain)
      question.  My trite answer to the implied trite question would be
      a simple "yes".</p>
    <p>I think you are asking something more sophisticated though?   If
      we believe that there are *some* kinds of changes to the brain
      (such as Dave's examples below) when we "change our minds" or "see
      things differently" then in fact there is a "plastic" change which
      persists past the direct effect of the drugs or the therapy
      session.   <br>
    </p>
    <p>I think you are asking *what* the specific brain changes are that
      might be effected through A) Therapy and B) Antidepressants/??? 
      and C) a) supported/enhanced/accelerated by b).  <br>
    </p>
    <p>I have no personal experience with B (excepting of course, the
      self-medication with alcohol, fats, carbs and mood-alterations
      that come with their timely application).  The experiences I have
      with A) ranging from a good bartender to a good life-partner to a
      good friend to a licensed therapist, suggest that significant
      changes *can* be made.   <br>
    </p>
    <p>Those made with a "casual" conversational partner under the
      influence of alcohol tend to be a lot more elastic.   I've never
      worked as a bartender but can imagine how much mood-swinging,
      life-change-claiming experiences they observe in their
      customers.   I've observed angry as well as sloppy drunks who seem
      to resolve their angst while "under the influence" only to return
      to roughly the same position with their angst the next day/weekend
      and go through the same alcohol/rant/rave induced denoument over
      (and over and over).  From what I've observed (less frequently)
      pot smokers, binge-eaters, binge-shoppers and gamblers go through
      a similar cycle.   <br>
    </p>
    <p>if/since the goal is often to effect more plastic change, then it
      is natural to seek mechanisms that support that.   I personally
      have tried some therapy and had mixed results.  I wasn't
      specifically seeking relief from depression as such, but
      depression was surely part of the complex of symptoms I was
      feeling.  I was seeking to make some "changes in perspective"
      which I hoped would lower the cognitive/emotional burden I was
      feeling from navigating my life as it was structured.   I was
      stuck in not wanting to change the structure of my life, finding
      aspects of it hard/tiring/confronting to endure, and wanting to
      "adjust my attitude" to fit my circumstances "more better".   Of
      course, the net result included recognizing that *some* of the
      aspects of my life *would change* as I changed my attitude toward
      them.   This included primary and secondary relationships, and
      work/career as well as my relationship with the larger social
      sphere as I apprehend it.    <br>
    </p>
    <p>Both therapists asked me  when I interviewed them if I was
      seeking anti-depressant medication.   I didn't know if that was A)
      them observing/diagnosing me as "depressed" on first meeting; B)
      vetting me for someone who also needed a consult with a licensed
      psychiatrist who could make such prescriptions; C) doing triage to
      see if my self-proclaimed reasons (which didn't include
      acknowledging depression) for seeking therapy were misleading (in
      that specific way); D) vetting me for someone who was seeking a
      "quick fix".   <br>
    </p>
    <p>The second therapist DID offer and provide me with some EMDR
      treatment (eye movement desensitization and reprocessing).  I was
      skeptical, but approached it as a mild form of hypnosis.   She was
      relatively new to the method and I was also perhaps "indulging
      her" in getting some practice while I got to experiment with
      whether such things *could* have an effect.   My (very subjective)
      answer was that it could absolutely be effective.   When it
      worked, I swear I felt an immediate (and mostly plastic) shift in
      my larger mental state.  It seemed to work as advertised in
      breaking some kinds of persistent beliefs I held about myself or
      the world.   One important caveat that is fundamental to the
      psychotheraputic model... it only worked when I really wanted it
      to.   The trick (not unlike some of my recent rants here about
      "asking the right question") seemed to be to frame the
      problem/question/belief at hand properly before we could actually
      effectively make any headway.    We often spent an entire session
      trying to agree on what the underlying "belief" I wanted/need to
      change *was* and then do the actual EMDR (including some pre and
      post analysis) in a subsequent session.  My therapist seemed a
      little frustrated at how much time/energy we expended narrowing it
      all down to "the right question" and we agreed this was at least
      *partly* a consequence of me living so strongly (belligerently?)
      in my head.   I think she also *learned* from my example that
      "getting the question right" was key.    It felt to me that the
      few successful EMDR sessions we had (small handful) DID help to
      unkink some of my deeper beliefs and I DID obtain some immediate
      and persistent relief in my life from it.  It may also be the case
      that since I wasn't seeking relief from any specific identifiable
      events or circumstances, that EMDR wasn't the perfect fit. <br>
    </p>
    <p>I brought up EMDR because I felt that it's mechanism (which is a
      little under-understood I think) may not be that dissimilar to
      conventional anti-depressant or complementarily? microdosing of
      psi drugs in that it helped me get *past* the built-in (ego?)
      defenses that were holding various beliefs in a sacred place.  
      From what I hear with conventional anti-depressants, they can
      relieve the psychic anxiety or increase the energy to a level that
      allows the individual to proceed to change habits which they might
      otherwise be unable to due to under/overproduction of
      neurochemistry.   I would suggest that the anti-depressant
      mechanisms change the *dynamics* of the brain which *allows* the
      function to shift enough that the *structure* can become changed
      through some amount of repetition (shift in habits of
      being/thinking) which would reflect the "change to the brain" you
      are suggesting.   I assume the same thing (through different
      mechanisms?) applies to psi microdosing.   Instead of adjusting
      the *gross* or *familiar* neurochemistry, they tweak more subtle
      (or lesser known?) mechanisms which allow for/induce behavioral
      (thought as well as activity) changes in a way that can lead to
      the brain-function/structure changes you are suggesting.</p>
    <p>On reflection, the EMDR experience I had *felt* like something
      shifted physically/biochemically very abruptly and plasticly.  I
      don't remember ever feeling like the beliefs I had "changed" were
      at risk of reverting.  In that way it felt like I'd achieved a <i>denoument</i>
      of some kind which I suppose doesn't have to represent significant
      physical changes?   <br>
    </p>
    <p>Mumble,</p>
    <p> - Steve<br>
    </p>
    <p><br>
    </p>
    <div class="moz-cite-prefix">On 3/8/19 9:36 AM, Prof David West
      wrote:<br>
    </div>
    <blockquote type="cite"
      cite="mid:4d4de3ce-dd03-4582-8369-1551ab04f803@www.fastmail.com">
      <meta http-equiv="content-type" content="text/html; charset=UTF-8">
      <title></title>
      <style type="text/css">#fastmail-quoted p.fastmail-quoted-MsoNormal,#fastmail-quoted  li.fastmail-quoted-MsoNormal,#fastmail-quoted  div.fastmail-quoted-MsoNormal{margin-top:0in;margin-right:0in;margin-left:0in;margin-bottom:0.0001pt;font-size:12pt;font-family:"Times New Roman", serif;}
#fastmail-quoted a:link,#fastmail-quoted  span.fastmail-quoted-MsoHyperlink{color:blue;text-decoration-line:underline;text-decoration-style:solid;text-decoration-color:currentcolor;}
#fastmail-quoted a:visited,#fastmail-quoted  span.fastmail-quoted-MsoHyperlinkFollowed{color:purple;text-decoration-line:underline;text-decoration-style:solid;text-decoration-color:currentcolor;}
#fastmail-quoted span.fastmail-quoted-EmailStyle17{font-family:"Calibri", sans-serif;color:rgb(31, 73, 125);}
#fastmail-quoted span.fastmail-quoted-EmailStyle18{font-family:"Calibri", sans-serif;color:rgb(153, 51, 102);}
#fastmail-quoted .fastmail-quoted-MsoChpDefault{font-size:10pt;}
#fastmail-quoted div.fastmail-quoted-WordSection1{}
#fastmail-quoted ol{margin-bottom:0in;}
#fastmail-quoted ul{margin-bottom:0in;}

p.MsoNormal,p.MsoNoSpacing{margin:0}</style>
      <div style="font-family:Arial;">Not necessarily "a crock."<br>
      </div>
      <div style="font-family:Arial;"><br>
      </div>
      <div style="font-family:Arial;">Pretend, anthropomorphize a bit,
        that the brain is an entity with at least three observable
        behaviors: 1) establishing and/or modifying physical 'circuits'
        in response to stimuli of category A; 2) 'activating' specific
        subsets of the overall circuitry in response to stimuli of
        category B; and 3) 'emitting' electromagnetic wave forms in
        response to stimuli of category C.<br>
      </div>
      <div style="font-family:Arial;"><br>
      </div>
      <div style="font-family:Arial;">Ignore for a moment the fact that
        all three categories of stimuli and all three behavioral
        responses probably occur simultaneously in most cases. [Maybe
        not the rewiring, as that seems to have multiple unique
        constraints.]<br>
      </div>
      <div style="font-family:Arial;"><br>
      </div>
      <div style="font-family:Arial;">We then collect a lot of data of
        the sort, stimulus X(n) evoked behavior Y, with Behavior Y being
        an instance of 'rewiring' (p), 'local activation' (q), or
        'emission' (r).<br>
      </div>
      <div style="font-family:Arial;"><br>
      </div>
      <div style="font-family:Arial;">If we observe that stimulus X(1)
        and stimulus X(6) evoke an instance of (p) we might, being a bit
        careless with our language, state that the two different stimuli
        "change the brain in the same way." Being a bit more careful, we
        might say only that Stimuli X(1) and X(6) belong in the same
        category A, B, or C.<br>
      </div>
      <div style="font-family:Arial;"><br>
      </div>
      <div style="font-family:Arial;">Given this framework, I would
        venture a guess that Therapy and Drugs, as stimuli, would not
        evoke the same behavior. I would expect Therapy to result in
        behaviors of the 'rewiring' type while Drugs evoke 'activation'
        type.<br>
      </div>
      <div style="font-family:Arial;"><br>
      </div>
      <div style="font-family:Arial;">This would allow me to address
        Nick's concern, "odd dualism by which some brain changes are
        REALLY brain changes and some are not" by asserting that there
        is no 'real/unreal' dualism, but there is a useful category
        distinction to be made.<br>
      </div>
      <div style="font-family:Arial;"><br>
      </div>
      <div style="font-family:Arial;">davew<br>
      </div>
      <div style="font-family:Arial;"><br>
      </div>
      <div style="font-family:Arial;"><br>
      </div>
      <div style="font-family:Arial;">On Thu, Mar 7, 2019, at 9:41 PM,
        Nick Thompson wrote:<br>
      </div>
      <blockquote type="cite" id="fastmail-quoted">
        <div class="fastmail-quoted-WordSection1">
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(153, 51, 102)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size">Sorry. 
                  See correction, below.  The point is, if the therapist
                  convinces the patient, by rational argument, to do the
                  Right Thing, whatever the right thing would be, we
                  don’t tend to think of this as a brain change.  But of
                  course it is.  So, what is this odd dualism by which
                  some brain changes are REALLY brain changes, and some
                  are not?  Thus, we see again, as we must always see,
                  (};-)] that brain state materialism is a crock. </span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(153, 51, 102)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size"> </span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(153, 51, 102)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size">N</span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(153, 51, 102)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size"> </span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(153, 51, 102)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size"> </span></span></span><br>
          </p>
          <div>
            <p class="fastmail-quoted-MsoNormal"><span
                style="color:rgb(153, 51, 102)" class="colour"><span
                  style="font-family:"Calibri", sans-serif"
                  class="font"><span style="font-size:11pt" class="size">Nicholas
                    S. Thompson</span></span></span><br>
            </p>
            <p class="fastmail-quoted-MsoNormal"><span
                style="color:rgb(153, 51, 102)" class="colour"><span
                  style="font-family:"Calibri", sans-serif"
                  class="font"><span style="font-size:11pt" class="size">Emeritus
                    Professor of Psychology and Biology</span></span></span><br>
            </p>
            <p class="fastmail-quoted-MsoNormal"><span
                style="color:rgb(153, 51, 102)" class="colour"><span
                  style="font-family:"Calibri", sans-serif"
                  class="font"><span style="font-size:11pt" class="size">Clark
                    University</span></span></span><br>
            </p>
            <p class="fastmail-quoted-MsoNormal"><span
                style="color:rgb(153, 51, 102)" class="colour"><span
                  style="font-family:"Calibri", sans-serif"
                  class="font"><span style="font-size:11pt" class="size"><a
href="http://home.earthlink.net/~nickthompson/naturaldesigns/"
                      moz-do-not-send="true"><span style="color:rgb(5,
                        99, 193)" class="colour">http://home.earthlink.net/~nickthompson/naturaldesigns/</span></a></span></span></span><br>
            </p>
          </div>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(153, 51, 102)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size"> </span></span></span><br>
          </p>
          <div>
            <div
style="border-right-color:currentcolor;border-right-style:none;border-right-width:medium;border-bottom-color:currentcolor;border-bottom-style:none;border-bottom-width:medium;border-left-color:currentcolor;border-left-style:none;border-left-width:medium;border-image-outset:0;border-image-repeat:stretch;border-image-slice:100%;border-image-source:none;border-image-width:1;border-top-color:rgb(225,
              225,
225);border-top-style:solid;border-top-width:1pt;padding-top:3pt;padding-right:0in;padding-bottom:0in;padding-left:0in;">
              <p class="fastmail-quoted-MsoNormal"><b><span
                    style="font-family:"Calibri", sans-serif"
                    class="font"><span style="font-size:11pt"
                      class="size">From:</span></span></b><span
                  style="font-family:"Calibri", sans-serif"
                  class="font"><span style="font-size:11pt" class="size">
                    Nick Thompson [<a class="moz-txt-link-freetext" href="mailto:nickthompson@earthlink.net">mailto:nickthompson@earthlink.net</a>] <br>
                    <b>Sent:</b> Thursday, March 07, 2019 8:30 PM<br>
                    <b>To:</b> 'The Friday Morning Applied Complexity
                    Coffee Group' <a class="moz-txt-link-rfc2396E" href="mailto:friam@redfish.com"><friam@redfish.com></a><br>
                    <b>Subject:</b> RE: [FRIAM] is this true?</span></span></p>
            </div>
          </div>
          <p class="fastmail-quoted-MsoNormal"> <br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(31, 73, 125)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size">Of
                  course therapy alters the brain.  How on earth else
                  could it work?  So, the question wouldn’t come up if
                  people didn’t suppose that some brain alterations <s>and</s>
                </span></span></span><b><i><span style="color:rgb(153,
                  51, 102)" class="colour"><span
                    style="font-family:"Calibri", sans-serif"
                    class="font"><span style="font-size:11pt"
                      class="size">[NST==>are<==nst] </span></span></span></i></b><span
              style="color:rgb(31, 73, 125)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size">not
                  REALLY brain alterations.  I don’t know how those
                  people make that distinction.</span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(31, 73, 125)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size"> </span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(31, 73, 125)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size">Nick</span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(31, 73, 125)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size"> </span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(31, 73, 125)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size">Nicholas
                  S. Thompson</span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(31, 73, 125)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size">Emeritus
                  Professor of Psychology and Biology</span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(31, 73, 125)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size">Clark
                  University</span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(31, 73, 125)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size"><a
href="http://home.earthlink.net/~nickthompson/naturaldesigns/"
                    moz-do-not-send="true"><span style="color:rgb(5, 99,
                      193)" class="colour">http://home.earthlink.net/~nickthompson/naturaldesigns/</span></a></span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><span
              style="color:rgb(31, 73, 125)" class="colour"><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size"> </span></span></span><br>
          </p>
          <p class="fastmail-quoted-MsoNormal"><b><span
                style="font-family:"Calibri", sans-serif"
                class="font"><span style="font-size:11pt" class="size">From:</span></span></b><span
              style="font-family:"Calibri", sans-serif"
              class="font"><span style="font-size:11pt" class="size">
                Friam [<a href="mailto:friam-bounces@redfish.com"
                  moz-do-not-send="true">mailto:friam-bounces@redfish.com</a>]
                <b>On Behalf Of </b>Frank Wimberly<br>
                <b>Sent:</b> Thursday, March 07, 2019 6:20 PM<br>
                <b>To:</b> The Friday Morning Applied Complexity Coffee
                Group <<a href="mailto:friam@redfish.com"
                  moz-do-not-send="true">friam@redfish.com</a>><br>
                <b>Subject:</b> Re: [FRIAM] is this true?</span></span></p>
          <p class="fastmail-quoted-MsoNormal"> <br>
          </p>
          <div>
            <div>
              <p class="fastmail-quoted-MsoNormal">Therapy and drugs can
                certainly change a life.  I had a friend who worked for
                a research organization at the University of
                Pittsburgh.  He had a Ph.D. in psychology.  At the time
                I worked in the Robotics Institute at Carnegie Mellon.
                He became interested in my work and wondered if there
                were opportunities for him there.  He investigated and
                was offered a position.  As a faculty member your job
                was to find a problem solve it and publish the results
                and then seek funding for further work but usually you
                had the freedom to pursue whatever problem you wanted to
                within reason.  He was not used to this lack of
                structure and he became unhappy.  One night he called me
                and was in desperate straits.  I did what it could to
                encourage him.   He entered therapy with a
                psychiatrist.  Over the months he became more
                productive.  After making some contributions in
                scheduling and planning software as I recall, he went to
                work for a startup and did some excellent work
                developing visualization tools.  He was head of a group
                of a dozen or more developers and scientists.  The group
                became a separate business.  After a couple of years it
                was bought by a fortune 50 company and he was made head
                of the division it became.<br>
              </p>
            </div>
            <div>
              <p class="fastmail-quoted-MsoNormal"> <br>
              </p>
            </div>
            <div>
              <p class="fastmail-quoted-MsoNormal">I don't know whether
                or how his brain changes but his life certainly did.<br>
              </p>
            </div>
            <div>
              <p class="fastmail-quoted-MsoNormal"> <br>
              </p>
            </div>
            <div>
              <p class="fastmail-quoted-MsoNormal">Frank<br>
              </p>
            </div>
          </div>
          <p class="fastmail-quoted-MsoNormal"> <br>
          </p>
          <div>
            <div>
              <p class="fastmail-quoted-MsoNormal">On Thu, Mar 7, 2019
                at 4:58 PM Prof David West <<a
                  href="mailto:profwest@fastmail.fm"
                  moz-do-not-send="true">profwest@fastmail.fm</a>>
                wrote:<br>
              </p>
            </div>
            <blockquote
style="border-top-color:currentcolor;border-top-style:none;border-top-width:medium;border-right-color:currentcolor;border-right-style:none;border-right-width:medium;border-bottom-color:currentcolor;border-bottom-style:none;border-bottom-width:medium;border-image-outset:0;border-image-repeat:stretch;border-image-slice:100%;border-image-source:none;border-image-width:1;border-left-color:rgb(204,
              204,
204);border-left-style:solid;border-left-width:1pt;padding-top:0in;padding-right:0in;padding-bottom:0in;padding-left:6pt;margin-left:4.8pt;margin-top:5pt;margin-right:0in;margin-bottom:5pt;">
              <div>
                <div>
                  <p class="fastmail-quoted-MsoNormal"><span
                      style="font-family:"Arial", sans-serif"
                      class="font">ketamine would not be the first drug
                      that was utilized to augment therapy. MDA, MDMA,
                      even LSD were all studied as ways to enhance,
                      optimize, therapy.</span><br>
                  </p>
                </div>
                <div>
                  <p class="fastmail-quoted-MsoNormal"><span
                      style="font-family:"Arial", sans-serif"
                      class="font"> </span><br>
                  </p>
                </div>
                <div>
                  <p class="fastmail-quoted-MsoNormal"><span
                      style="font-family:"Arial", sans-serif"
                      class="font">An therapy, some kinds of it anyway,
                      have also been demonstrated to produce very mild
                      altered states of consciousness — somewhat less
                      than hypnosis, somewhat greater than attending an
                      old fashioned Catholic Mass.</span><br>
                  </p>
                </div>
                <div>
                  <p class="fastmail-quoted-MsoNormal"><span
                      style="font-family:"Arial", sans-serif"
                      class="font"> </span><br>
                  </p>
                </div>
                <div>
                  <p class="fastmail-quoted-MsoNormal"><span
                      style="font-family:"Arial", sans-serif"
                      class="font">davew</span><br>
                  </p>
                </div>
                <div>
                  <p class="fastmail-quoted-MsoNormal"><span
                      style="font-family:"Arial", sans-serif"
                      class="font"> </span><br>
                  </p>
                </div>
                <div>
                  <p class="fastmail-quoted-MsoNormal"><span
                      style="font-family:"Arial", sans-serif"
                      class="font"> </span><br>
                  </p>
                </div>
                <div>
                  <p class="fastmail-quoted-MsoNormal"><span
                      style="font-family:"Arial", sans-serif"
                      class="font">On Thu, Mar 7, 2019, at 3:25 PM, glen
                    </span><span style="font-family:"Cambria
                      Math", serif" class="font">∅</span><span
                      style="font-family:"Arial", sans-serif"
                      class="font"> wrote:</span><br>
                  </p>
                </div>
                <blockquote
                  id="fastmail-quoted-gmail-m_362131261802491436fastmail-quoted"
                  style="margin-top:5pt;margin-bottom:5pt;">
                  <div>
                    <p class="fastmail-quoted-MsoNormal">From <a
href="https://www.nytimes.com/2019/03/07/opinion/ketamine-depression.html"
                        moz-do-not-send="true">https://www.nytimes.com/2019/03/07/opinion/ketamine-depression.html</a><br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal">> After all,
                      therapy and prescription drugs like
                      antidepressants change the brain in surprisingly
                      similar ways.<br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal"> <br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal">Does therapy
                      exhibit changes in the brain similar to drugs
                      (like antidepressants or not)?  I wish the author
                      had provided a citation or 2.<br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal"> <br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal"> <br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal">============================================================<br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal">FRIAM Applied
                      Complexity Group listserv<br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal">Meets Fridays
                      9a-11:30 at cafe at St. John's College<br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal">to unsubscribe
                      <a
                        href="http://redfish.com/mailman/listinfo/friam_redfish.com"
                        moz-do-not-send="true">http://redfish.com/mailman/listinfo/friam_redfish.com</a><br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal">archives back
                      to 2003: <a
                        href="http://friam.471366.n2.nabble.com/"
                        moz-do-not-send="true">http://friam.471366.n2.nabble.com/</a><br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal">FRIAM-COMIC <a
                        href="http://friam-comic.blogspot.com/"
                        moz-do-not-send="true">http://friam-comic.blogspot.com/</a>
                      by Dr. Strangelove<br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal"> <br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal"> <br>
                    </p>
                  </div>
                  <div>
                    <p class="fastmail-quoted-MsoNormal"><b>Attachments:</b><br>
                    </p>
                  </div>
                  <ul type="disc">
                    <li style="" class="fastmail-quoted-MsoNormal">pEpkey.asc<br>
                    </li>
                  </ul>
                </blockquote>
                <div>
                  <p class="fastmail-quoted-MsoNormal"><span
                      style="font-family:"Arial", sans-serif"
                      class="font"> </span><br>
                  </p>
                </div>
              </div>
              <div style="font-family:Arial;">============================================================<br>
              </div>
              <div style="font-family:Arial;">FRIAM Applied Complexity
                Group listserv<br>
              </div>
              <div style="font-family:Arial;">Meets Fridays 9a-11:30 at
                cafe at St. John's College<br>
              </div>
              <div style="font-family:Arial;">to unsubscribe <a
                  href="http://redfish.com/mailman/listinfo/friam_redfish.com"
                  moz-do-not-send="true">http://redfish.com/mailman/listinfo/friam_redfish.com</a><br>
              </div>
              <div style="font-family:Arial;">archives back to 2003: <a
                  href="http://friam.471366.n2.nabble.com/"
                  moz-do-not-send="true">http://friam.471366.n2.nabble.com/</a><br>
              </div>
              <div style="font-family:Arial;">FRIAM-COMIC <a
                  href="http://friam-comic.blogspot.com/"
                  moz-do-not-send="true">http://friam-comic.blogspot.com/</a>
                by Dr. Strangelove<br>
              </div>
            </blockquote>
          </div>
          <div style="font-family:Arial;"><br>
          </div>
          <div style="font-family:Arial;"><br>
          </div>
          <div style="font-family:Arial;">--<br>
          </div>
          <div>
            <div style="font-family:Arial;">Frank Wimberly<br>
            </div>
            <div style="font-family:Arial;">140 Calle Ojo Feliz<br>
            </div>
            <div style="font-family:Arial;">Santa Fe, NM 87505<br>
            </div>
            <div style="font-family:Arial;">505 670-9918<br>
            </div>
          </div>
        </div>
        <div>============================================================<br>
        </div>
        <div>FRIAM Applied Complexity Group listserv<br>
        </div>
        <div>Meets Fridays 9a-11:30 at cafe at St. John's College<br>
        </div>
        <div>to unsubscribe
          <a class="moz-txt-link-freetext" href="http://redfish.com/mailman/listinfo/friam_redfish.com">http://redfish.com/mailman/listinfo/friam_redfish.com</a><br>
        </div>
        <div>archives back to 2003: <a class="moz-txt-link-freetext" href="http://friam.471366.n2.nabble.com/">http://friam.471366.n2.nabble.com/</a><br>
        </div>
        <div>FRIAM-COMIC <a class="moz-txt-link-freetext" href="http://friam-comic.blogspot.com/">http://friam-comic.blogspot.com/</a> by Dr.
          Strangelove<br>
        </div>
        <div><br>
        </div>
      </blockquote>
      <div style="font-family:Arial;"><br>
      </div>
      <br>
      <fieldset class="mimeAttachmentHeader"></fieldset>
      <pre class="moz-quote-pre" wrap="">============================================================
FRIAM Applied Complexity Group listserv
Meets Fridays 9a-11:30 at cafe at St. John's College
to unsubscribe <a class="moz-txt-link-freetext" href="http://redfish.com/mailman/listinfo/friam_redfish.com">http://redfish.com/mailman/listinfo/friam_redfish.com</a>
archives back to 2003: <a class="moz-txt-link-freetext" href="http://friam.471366.n2.nabble.com/">http://friam.471366.n2.nabble.com/</a>
FRIAM-COMIC <a class="moz-txt-link-freetext" href="http://friam-comic.blogspot.com/">http://friam-comic.blogspot.com/</a> by Dr. Strangelove
</pre>
    </blockquote>
  </body>
</html>