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<div style="font-family:sans-serif"><div style="white-space:normal"><p dir="auto">There used to be a lot of talk about “junk DNA” which doesn’t do anything, but I’ve gotten the impression (sorry, I can’t give references) that more recently the “junk DNA” does play a role.</p>
<p dir="auto">Also, adjacency or propinquity of genes on a chromosome affects evolution (if I get one of the genes from a parent, I’m highly likely to get the other also). I have no idea if it plays a role during the life of a cell. I don’t know anything about how sexual reproduction goes about building a new chromosome by selecting pieces from the chromosomes of the parents, but on the face of it, changing the layout (or in mathematical terms, the metric) could lead to omission or duplication errors in the result.</p>
<p dir="auto">TL;DR Be careful what you wish for.</p>
<p dir="auto">—Barry</p>
<br><p dir="auto">On 22 Jan 2021, at 18:37, Marcus Daniels wrote:</p>
<blockquote style="border-left:2px solid #777; color:#777; margin:0 0 5px; padding-left:5px"><p dir="auto">Most of the human genome doesn't express as proteins, so there should be lots of room to store stuff.<br>
Such technology is hardly science fiction, it's even FDA approved!<br>
<br>
<a href="https://www.fda.gov/news-events/press-announcements/fda-approves-novel-gene-therapy-treat-patients-rare-form-inherited-vision-loss" style="color:#777">https://www.fda.gov/news-events/press-announcements/fda-approves-novel-gene-therapy-treat-patients-rare-form-inherited-vision-loss</a><br>
<br>
-----Original Message-----<br>
From: Friam <friam-bounces@redfish.com> On Behalf Of Prof David West<br>
Sent: Friday, January 22, 2021 2:43 PM<br>
To: friam@redfish.com<br>
Subject: [FRIAM] tangent from uncanny valley<br>
<br>
The idea of posthuman came up (yes it was me) in another thread. This article <a href="https://www.nature.com/articles/s41589-020-00711-4" style="color:#777">https://www.nature.com/articles/s41589-020-00711-4</a> opens an interesting door: "reprogramming" DNA by inserting new data into living DNA. After all a program is just another form of data. This might be orthogonal to genetic (re)engineering.<br>
<br>
davew<br>
<br>
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