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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link="#0563C1" vlink="#954F72" style='word-wrap:break-word'><div class=WordSection1><p class=MsoNormal>Jon, et. al, <o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal>I love it when you guys talk dirty!<o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal>I am afraid I won’t be able to make it Friday (travel angst), so could somebody explain in a few sentences what is going on, here? <o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal>See you all NEXT Friday. <o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal>Nick <o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal>Nick Thompson<o:p></o:p></p><p class=MsoNormal><a href="mailto:ThompNickSon2@gmail.com">ThompNickSon2@gmail.com</a><o:p></o:p></p><p class=MsoNormal><a href="https://wordpress.clarku.edu/nthompson/">https://wordpress.clarku.edu/nthompson/</a><o:p></o:p></p><p class=MsoNormal><o:p> </o:p></p><div style='border:none;border-top:solid #E1E1E1 1.0pt;padding:3.0pt 0in 0in 0in'><p class=MsoNormal><b>From:</b> Friam <friam-bounces@redfish.com> <b>On Behalf Of </b>Jon Zingale<br><b>Sent:</b> Wednesday, October 13, 2021 12:54 PM<br><b>To:</b> friam@redfish.com<br><b>Subject:</b> Re: [FRIAM] Schwill Rock?<o:p></o:p></p></div><p class=MsoNormal><o:p> </o:p></p><div><div><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Verdana",sans-serif;color:#333333'>Thanks Roger, Marcus. I am a newbie in this area and so it might be good for me to ask some potentially obvious questions about SMILES (since they are used everywhere).<o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Verdana",sans-serif;color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Verdana",sans-serif;color:#333333'>1. Is the SMILES isomorphism problem equivalent to the graph isomorphism problem, or is there some advantage from being context free parsable?<o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Verdana",sans-serif;color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Verdana",sans-serif;color:#333333'>2. In practice, do the edge cases that Roger mentioned effectively get added into the rewrite rules for the grammar or are they a separate kind of thing?<o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Verdana",sans-serif;color:#333333'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Verdana",sans-serif;color:#333333'>3. How is chirality handled?<o:p></o:p></span></p></div></div></div></body></html>