<div dir="auto">I am the geek guy for a small nonprofit foundation here in Ecuador and I must say that at least a few software companies are fairly generous with licensing for academic and nonprofit organizations. Microsoft has been particularly helpful. </div><div><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">On Tue, Jul 26, 2022 at 8:48 PM Jon Zingale <<a href="mailto:jonzingale@gmail.com">jonzingale@gmail.com</a>> wrote:<br></div><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div dir="ltr"><div class="gmail_default" style="font-family:verdana,sans-serif;font-size:small;color:#333333">"""Current in silico software is only accessible to large pharmaceutical companies willing to pay obnoxious licensing fees. Students in every country no matter their university, startup companies to Fortune 500s, and even dedicated hobbyists will all have the same opportunity to design new molecules to change the future of drug discovery," said Shkreli, co-founder of Druglike."""<br></div><div class="gmail_default" style="font-family:verdana,sans-serif;font-size:small;color:#333333"><br></div><div class="gmail_default" style="font-family:verdana,sans-serif;font-size:small;color:#333333">FWIW, my company's software is free to academics. This article hides the fact that the majority of the economic barrier to entry is not licensing but the cost of performing the large-scale simulations necessary to do docking, md, generating conformers, or what-have-you. Drug discovery is computationally hard and if AWS or whoever is going to ultimately charge for compute then someone along the path will need to pay for that compute. Just my two cents.</div></div>
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