[FRIAM] CD3+, CD4+, CD8+

[uǝlƃ ☣]

Suppressed T cell-mediated immunity in patients with COVID-19: A clinical retrospective study in Wuhan, China
https://www.journalofinfection.com/article/S0163-4453(20)30223-1/abstract

Does anyone here have a sense for the types of conditions (cf covid19 comorbidities) that cluster around all 3 proteins? My naive googling returns comments about graft-vs-host and various autoimmune conditions and immunosuppressive therapies. But I'm having trouble getting a feel for how they might all cluster together. Maybe it's simply that lower amounts of *any* of the 3 subsets produces a higher risk for those with covid19? But I keep hearing that the "cytokine storm" is more than just an effect, it may loop back and be part of the problem.

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