[FRIAM] the synthetic spike, again

[Pieter Steenekamp]

So there are different opinions out there. Check!

On Fri, 2 Jul 2021 at 15:13, uǝlƃ ☤>$ <gepropella at gmail.com> wrote:

> COVID-19 Vaccine-Generated Spike Protein is Safe, Contrary to Viral Claims
>
> https://www.factcheck.org/2021/07/scicheck-covid-19-vaccine-generated-spike-protein-is-safe-contrary-to-viral-claims/
>
> "That’s because the SARS-CoV-2 spike protein is a shape-shifter. To fuse
> its viral membrane with the host cell membrane it substantially changes its
> shape from an unstable pre-fusion state to a stable post-fusion state.
> While previously working on a vaccine for MERS, a disease caused by another
> coronavirus, McLellan and others discovered that by adding two proline
> molecules to the spike protein, they could lock it into its pre-fusion
> state, triggering a more effective immune response and preventing cell
> entry. The same harmless mutation, called 2P, as in two proline molecules,
> is used in the SARS-CoV-2 vaccines.
>
> During a SARS-CoV-2 infection, the NIAID told us, the virus spike proteins
> can latch onto human cells, allowing the virus to infect them. With the
> live virus, the protein “attaches to receptors on the surface of cells and
> fuses the viral membrane with the host-cell membrane,” McLellan said.
>
> However, vaccine-generated spike proteins can’t do that fusion because
> they are locked in the pre-fusion shape."
>
> --
> ☤>$ uǝlƃ
>
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