[FRIAM] The lies of Trump and ecDNA

glen gepropella at gmail.com
Tue Feb 27 13:25:13 EST 2024

IDK. It seems like ecDNA, in general, can be either good or bad. And mitochondrial DNA feels like a boon, overall. Maybe a better analogy would be ecDNA <-> media and MAGA to the oncogenes being promoted. I think a useful foil for stressing the analogy is the difference between a filter bubble and an echo chamber. If we define a filter bubble as the sieve through which the ambience extrudes and an echo chamber as an agent-oriented selection bias, we can classify MAGA cult members as victims (incompetent consumers of media) and perpetrators. The perpetrators might be like the Federalist Society, where they seek echoes of their beliefs and put them in power. Or they might be like Joe Rogan, where they promote/amplify toxic materials they find in the wild. The latter seem like trans-acting ecDNA ... and Rachel Maddow might be similar to Joe Rogan in that sense, only considered toxic based on what they promote, not promotion in itself. The former seem like oncogenes. The rest, like some random soccer mom at the Jan 6 riot, don't seem like either of those to me.

On 2/27/24 08:51, Jochen Fromm wrote:
> The lies of Trump and his MAGA cult are a bit like extrachromosomal DNA that is apparently behind many malignant cancers. Both are normally part of selfish entities - single cell organisms or narcissistic con men -  and disrupt or distort the normal fabric of the world they live in. Interestingly ecDNA takes the form of tiny circles just like plasmids in bacteria. And it spreads faster than DNA in chromosomes, just as lies spread faster than the truth. As Jonathan Swift said "Falsehood flies, and truth comes limping after it"
> https://www.the-scientist.com/cancer-may-be-driven-by-dna-outside-of-chromosomes-68590

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