[FRIAM] tangent from uncanny valley

[Barry MacKichan]

Hmmmmm…… ok

On 25 Jan 2021, at 11:59, Marcus Daniels wrote:

> I think a lot of that could be sorted out from population-based 
> statistical inference from whole genome sequencing and large biobanks.
>
> From: Friam <friam-bounces at redfish.com> On Behalf Of Barry MacKichan
> Sent: Monday, January 25, 2021 8:09 AM
> To: The Friday Morning Applied Complexity Coffee Group 
> <friam at redfish.com>
> Subject: Re: [FRIAM] tangent from uncanny valley
>
>
> There used to be a lot of talk about “junk DNA” which doesn’t do 
> anything, but I’ve gotten the impression (sorry, I can’t give 
> references) that more recently the “junk DNA” does play a role.
>
> Also, adjacency or propinquity of genes on a chromosome affects 
> evolution (if I get one of the genes from a parent, I’m highly 
> likely to get the other also). I have no idea if it plays a role 
> during the life of a cell. I don’t know anything about how sexual 
> reproduction goes about building a new chromosome by selecting pieces 
> from the chromosomes of the parents, but on the face of it, changing 
> the layout (or in mathematical terms, the metric) could lead to 
> omission or duplication errors in the result.
>
> TL;DR Be careful what you wish for.
>
> —Barry
>
>
> On 22 Jan 2021, at 18:37, Marcus Daniels wrote:
>
> Most of the human genome doesn't express as proteins, so there should 
> be lots of room to store stuff.
> Such technology is hardly science fiction, it's even FDA approved!
>
> https://www.fda.gov/news-events/press-announcements/fda-approves-novel-gene-therapy-treat-patients-rare-form-inherited-vision-loss
>
> -----Original Message-----
> From: Friam 
> <friam-bounces at redfish.com<mailto:friam-bounces at redfish.com>> On 
> Behalf Of Prof David West
> Sent: Friday, January 22, 2021 2:43 PM
> To: friam at redfish.com<mailto:friam at redfish.com>
> Subject: [FRIAM] tangent from uncanny valley
>
> The idea of posthuman came up (yes it was me) in another thread. This 
> article https://www.nature.com/articles/s41589-020-00711-4 opens an 
> interesting door: "reprogramming" DNA by inserting new data into 
> living DNA. After all a program is just another form of data. This 
> might be orthogonal to genetic (re)engineering.
>
> davew
>
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