[FRIAM] gen'fur

[Steve Smith]

Sometimes all you need is a good aphorism

    https://sketchplanations.com/goodharts-law

or maybe boost it up with a cartoon

    https://sketchplanations.com/

> I can't help but wonder if there's an analog of Goodhart's law lurking, here.
>
>
> On September 9, 2021 2:31:39 PM PDT, Marcus Daniels <marcus at snoutfarm.com> wrote:
>> Or they are reprogramming their people to be smarter!
>> (Actually, deCODE is owned by Amgen now.)
>>
>> Selection is already occurring, so it isn't as if this is some sci-fi thing.
>>
>> https://www.theatlantic.com/magazine/archive/2020/12/the-last-children-of-down-syndrome/616928/
>> -----Original Message-----
>> From: Friam <friam-bounces at redfish.com> On Behalf Of David Eric Smith
>> Sent: Thursday, September 9, 2021 2:12 PM
>> To: The Friday Morning Applied Complexity Coffee Group <friam at redfish.com>
>> Subject: Re: [FRIAM] gen'fur
>>
>> Aha!  This is why Iceland has the highest per-capita fraction of published authors in the world.  I had assumed it was the weather….
>>
>>> On Sep 10, 2021, at 2:17 AM, Marcus Daniels <marcus at snoutfarm.com> wrote:
>>>
>>> That can be screened as well with a large population-wide survey such has been done in the UK or Iceland.
>>> Of course, it is unlikely that complex behaviors will be governed by isolated mutations, so the task is to look for highly predictive motifs (e.g. regular expressions).  
>>>
>>> -----Original Message-----
>>> From: Friam <friam-bounces at redfish.com> On Behalf Of u?l? ?>$
>>> Sent: Thursday, September 9, 2021 10:12 AM
>>> To: friam at redfish.com
>>> Subject: Re: [FRIAM] gen'fur
>>>
>>> Ha! Now you're trolling. The answer is: "because the sites that generate reading ability (or whatever) *also* generate other 'abilities'", with "abilities" in scare quotes because many abilities are considered bad ... like the ability of a pimply faced white dude to shoot up a church or blow up a federal building.
>>>
>>> In addition to polyphenism, there's robustness. If more than 1 site generates the same functional ability (reading), then do we write them all? ... just one of them? ... a probabilistically predictive handful of them?
>>>
>>> On 9/9/21 10:00 AM, Marcus Daniels wrote:
>>>> So find the sites that correspond to reading ability, or whatever, and WRITE them.  
>>>>
>>>> -----Original Message-----
>>>> From: Friam <friam-bounces at redfish.com> On Behalf Of u?l? ?>$
>>>> Sent: Thursday, September 9, 2021 9:51 AM
>>>> To: friam at redfish.com
>>>> Subject: Re: [FRIAM] gen'fur
>>>>
>>>> I was alerted to this article this morning:
>>>>
>>>> Can Progressives Be Convinced That Genetics Matters?
>>>> https://www.newyorker.com/magazine/2021/09/13/can-progressives-be-con
>>>> v
>>>> inced-that-genetics-matters
>>>>
>>>> It should delight those amongst us who rant about the "woke". 8^D But it dovetails nicely with the fraught concept of equality in the other thread.
>>>>
>>>> Coincidentally, also on 9/6, the BIAPT announced their early career prize winner Emily McTernan:
>>>> https://linkprotect.cudasvc.com/url?a=https%3a%2f%2fwww.associationfo
>>>> rpoliticalthought.ac.uk%2fbiapt-2021-early-care&c=E,1,Je9MVNdO8lpJQOd
>>>> 6fZwUNe-4z5yuFq0upxNIzMBFjmLFh_h5a63ueVVpd8lkEdWeUx5Xx1RaoPg3T5Ph8YlG
>>>> 0558qqHLZD8-DKeBPEC3YYM,&typo=1
>>>> er-prize-winner-dr-emily-mcternan/
>>>>
>>>> "In her forthcoming monograph, Dr McTernan develops her work on social equality further, to advance a pioneering conceptual account – and robust normative defence – of the phenomenon of ‘taking offence’. Therein, McTernan contends, we should understand taking offence, under appropriate conditions, as a civic virtue rather than a vice, as an emotion that embodies the resistance of social inequalities within a community."
>>>>
>>>>
>>>> On 9/8/21 8:06 PM, Marcus Daniels wrote:
>>>>> From about a cancer rate of 10% (without mutation) to 50% (with) but it depends on the BRCA variant.
>>>>>
>>>>> https://www.cdc.gov/genomics/disease/breast_ovarian_cancer/breast_ca
>>>>> n
>>>>> c
>>>>> er.htm
>>>>> <https://www.cdc.gov/genomics/disease/breast_ovarian_cancer/breast_c
>>>>> a
>>>>> n
>>>>> cer.htm>
>>>>>
>>>>>> On Sep 8, 2021, at 4:07 PM, Frank Wimberly <wimberly3 at gmail.com> wrote:
>>>>>>
>>>>>> 
>>>>>> Is the Braca gene that little correlated with breast cancer?
>>>>>>
>>>>>> ---
>>>>>> Frank C. Wimberly
>>>>>> 140 Calle Ojo Feliz,
>>>>>> Santa Fe, NM 87505
>>>>>>
>>>>>> 505 670-9918
>>>>>> Santa Fe, NM
>>>>>>
>>>>>> On Wed, Sep 8, 2021, 4:57 PM Marcus Daniels <marcus at snoutfarm.com <mailto:marcus at snoutfarm.com>> wrote:
>>>>>>
>>>>>>    Yeah, it is hard to get excited about “unusual” variance. Modern 
>>>>>> classification algorithms like gradient boosting make it possible 
>>>>>> to predict phenotypes, and to me that is a lot more interesting 
>>>>>> (and still possible to deconstruct).____
>>>>>>
>>>>>>    __ __
>>>>>>
>>>>>>    *From:* Friam <friam-bounces at redfish.com <mailto:friam-bounces at redfish.com>> *On Behalf Of *Eric Charles
>>>>>>    *Sent:* Wednesday, September 8, 2021 3:53 PM
>>>>>>    *To:* The Friday Morning Applied Complexity Coffee Group <friam at redfish.com <mailto:friam at redfish.com>>
>>>>>>    *Subject:* [FRIAM] gen'fur____
>>>>>>
>>>>>>    __ __
>>>>>>
>>>>>>    Gen'fur this, gen'fur that... and also the realities of biological complexity.... 
>>>>>>    ____
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