[FRIAM] tangent from uncanny valley

[Barry MacKichan]

There used to be a lot of talk about “junk DNA” which doesn’t do 
anything, but I’ve gotten the impression (sorry, I can’t give 
references) that more recently the “junk DNA” does play a role.

Also, adjacency or propinquity of genes on a chromosome affects 
evolution (if I get one of the genes from a parent, I’m highly likely 
to get the other also). I have no idea if it plays a role during the 
life of a cell. I don’t know anything about how sexual reproduction 
goes about building a new chromosome by selecting pieces from the 
chromosomes of the parents, but on the face of it, changing the layout 
(or in mathematical terms, the metric) could lead to omission or 
duplication errors in the result.

TL;DR Be careful what you wish for.

—Barry


On 22 Jan 2021, at 18:37, Marcus Daniels wrote:

> Most of the human genome doesn't express as proteins, so there should 
> be lots of room to store stuff.
> Such technology is hardly science fiction, it's even FDA approved!
>
> https://www.fda.gov/news-events/press-announcements/fda-approves-novel-gene-therapy-treat-patients-rare-form-inherited-vision-loss
>
> -----Original Message-----
> From: Friam <friam-bounces at redfish.com> On Behalf Of Prof David West
> Sent: Friday, January 22, 2021 2:43 PM
> To: friam at redfish.com
> Subject: [FRIAM] tangent from uncanny valley
>
> The idea of posthuman came up (yes it was me) in another thread. This 
> article https://www.nature.com/articles/s41589-020-00711-4 opens an 
> interesting door: "reprogramming" DNA by inserting new data into 
> living DNA. After all a program is just another form of data. This 
> might be orthogonal to genetic (re)engineering.
>
> davew
>
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