[FRIAM] gen'fur

[Marcus Daniels]

Puppies are adorable.

From: Friam <friam-bounces at redfish.com> On Behalf Of Frank Wimberly
Sent: Thursday, September 9, 2021 4:33 PM
To: The Friday Morning Applied Complexity Coffee Group <friam at redfish.com>
Subject: Re: [FRIAM] gen'fur

Down's babies are adorable.
---
Frank C. Wimberly
140 Calle Ojo Feliz,
Santa Fe, NM 87505

505 670-9918
Santa Fe, NM

On Thu, Sep 9, 2021, 3:32 PM Marcus Daniels <marcus at snoutfarm.com<mailto:marcus at snoutfarm.com>> wrote:
Or they are reprogramming their people to be smarter!
(Actually, deCODE is owned by Amgen now.)

Selection is already occurring, so it isn't as if this is some sci-fi thing.

https://www.theatlantic.com/magazine/archive/2020/12/the-last-children-of-down-syndrome/616928/
-----Original Message-----
From: Friam <friam-bounces at redfish.com<mailto:friam-bounces at redfish.com>> On Behalf Of David Eric Smith
Sent: Thursday, September 9, 2021 2:12 PM
To: The Friday Morning Applied Complexity Coffee Group <friam at redfish.com<mailto:friam at redfish.com>>
Subject: Re: [FRIAM] gen'fur

Aha!  This is why Iceland has the highest per-capita fraction of published authors in the world.  I had assumed it was the weather….

> On Sep 10, 2021, at 2:17 AM, Marcus Daniels <marcus at snoutfarm.com<mailto:marcus at snoutfarm.com>> wrote:
>
> That can be screened as well with a large population-wide survey such has been done in the UK or Iceland.
> Of course, it is unlikely that complex behaviors will be governed by isolated mutations, so the task is to look for highly predictive motifs (e.g. regular expressions).
>
> -----Original Message-----
> From: Friam <friam-bounces at redfish.com<mailto:friam-bounces at redfish.com>> On Behalf Of u?l? ?>$
> Sent: Thursday, September 9, 2021 10:12 AM
> To: friam at redfish.com<mailto:friam at redfish.com>
> Subject: Re: [FRIAM] gen'fur
>
> Ha! Now you're trolling. The answer is: "because the sites that generate reading ability (or whatever) *also* generate other 'abilities'", with "abilities" in scare quotes because many abilities are considered bad ... like the ability of a pimply faced white dude to shoot up a church or blow up a federal building.
>
> In addition to polyphenism, there's robustness. If more than 1 site generates the same functional ability (reading), then do we write them all? ... just one of them? ... a probabilistically predictive handful of them?
>
> On 9/9/21 10:00 AM, Marcus Daniels wrote:
>> So find the sites that correspond to reading ability, or whatever, and WRITE them.
>>
>> -----Original Message-----
>> From: Friam <friam-bounces at redfish.com<mailto:friam-bounces at redfish.com>> On Behalf Of u?l? ?>$
>> Sent: Thursday, September 9, 2021 9:51 AM
>> To: friam at redfish.com<mailto:friam at redfish.com>
>> Subject: Re: [FRIAM] gen'fur
>>
>> I was alerted to this article this morning:
>>
>> Can Progressives Be Convinced That Genetics Matters?
>> https://www.newyorker.com/magazine/2021/09/13/can-progressives-be-con
>> v
>> inced-that-genetics-matters
>>
>> It should delight those amongst us who rant about the "woke". 8^D But it dovetails nicely with the fraught concept of equality in the other thread.
>>
>> Coincidentally, also on 9/6, the BIAPT announced their early career prize winner Emily McTernan:
>> https://linkprotect.cudasvc.com/url?a=https%3a%2f%2fwww.associationfo
>> rpoliticalthought.ac.uk<http://rpoliticalthought.ac.uk>%2fbiapt-2021-early-care&c=E,1,Je9MVNdO8lpJQOd
>> 6fZwUNe-4z5yuFq0upxNIzMBFjmLFh_h5a63ueVVpd8lkEdWeUx5Xx1RaoPg3T5Ph8YlG
>> 0558qqHLZD8-DKeBPEC3YYM,&typo=1
>> er-prize-winner-dr-emily-mcternan/
>>
>> "In her forthcoming monograph, Dr McTernan develops her work on social equality further, to advance a pioneering conceptual account – and robust normative defence – of the phenomenon of ‘taking offence’. Therein, McTernan contends, we should understand taking offence, under appropriate conditions, as a civic virtue rather than a vice, as an emotion that embodies the resistance of social inequalities within a community."
>>
>>
>> On 9/8/21 8:06 PM, Marcus Daniels wrote:
>>> From about a cancer rate of 10% (without mutation) to 50% (with) but it depends on the BRCA variant.
>>>
>>> https://www.cdc.gov/genomics/disease/breast_ovarian_cancer/breast_ca
>>> n
>>> c
>>> er.htm
>>> <https://www.cdc.gov/genomics/disease/breast_ovarian_cancer/breast_c
>>> a
>>> n
>>> cer.htm>
>>>
>>>> On Sep 8, 2021, at 4:07 PM, Frank Wimberly <wimberly3 at gmail.com<mailto:wimberly3 at gmail.com>> wrote:
>>>>
>>>> 
>>>> Is the Braca gene that little correlated with breast cancer?
>>>>
>>>> ---
>>>> Frank C. Wimberly
>>>> 140 Calle Ojo Feliz,
>>>> Santa Fe, NM 87505
>>>>
>>>> 505 670-9918
>>>> Santa Fe, NM
>>>>
>>>> On Wed, Sep 8, 2021, 4:57 PM Marcus Daniels <marcus at snoutfarm.com<mailto:marcus at snoutfarm.com> <mailto:marcus at snoutfarm.com<mailto:marcus at snoutfarm.com>>> wrote:
>>>>
>>>>    Yeah, it is hard to get excited about “unusual” variance. Modern
>>>> classification algorithms like gradient boosting make it possible
>>>> to predict phenotypes, and to me that is a lot more interesting
>>>> (and still possible to deconstruct).____
>>>>
>>>>    __ __
>>>>
>>>>    *From:* Friam <friam-bounces at redfish.com<mailto:friam-bounces at redfish.com> <mailto:friam-bounces at redfish.com<mailto:friam-bounces at redfish.com>>> *On Behalf Of *Eric Charles
>>>>    *Sent:* Wednesday, September 8, 2021 3:53 PM
>>>>    *To:* The Friday Morning Applied Complexity Coffee Group <friam at redfish.com<mailto:friam at redfish.com> <mailto:friam at redfish.com<mailto:friam at redfish.com>>>
>>>>    *Subject:* [FRIAM] gen'fur____
>>>>
>>>>    __ __
>>>>
>>>>    Gen'fur this, gen'fur that... and also the realities of biological complexity....
>>>>    ____
>
>
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